bioscience

In recent years, Gamma delta (γδ) T cells have become a potential avenue for adoptive immunotherapy. To date, a number of clinical trials have used γδ T cells for cancer treatment. And this type of cell has special characteristics: MHC-unrestricted cytotoxicity, the ability to secrete inflammatory cytokines, the ability to distinguish transformed cells from normal cells, as well as the ability to promote the formation of antigen-specific CD81 and CD41 T cell responses. Due to the important function of γδ T cells in several diseases, it is necessary to develop suitable clinical assays for γδ T cell activity and cytotoxicity.Creative Biolabs is a leader in the research of γδ T cells and cancer immunotherapy. We provide comprehensive <a href="https://gammadelta-t-therapy.creative-biolabs.com/t-cell-cytotoxicity-test.htm" target="_blank" rel="noreferrer" class="article__link">γδ T cell cytotoxicity test services</a>, including LDH cytotoxicity test, flow cytometry-based cytotoxicity test, chromium-51 release assay, impedance-based label-free real-time cytotoxicity assay…

gammadelta T Cell Cytotoxicity Test

In gene delivery, non-viral vectors have become the preferred carrier system for DNA delivery. They can overcome major viral problems, such as immunogenicity and mutagenicity. Cationic lipid-mediated gene transfer is one of the most commonly used non-viral vectors and has been shown to be a safe and effective vector. [Cationic liposome](https://www.creative-biolabs.com/lipid-based-delivery/cationic-liposome-development-service.htm) is a structure made of positively charged lipids. Because of their good interaction with negatively charged DNA and cell membranes, they are increasingly being studied for gene therapy. They have demonstrated their selectivity to tumor vascular endothelial cells, which brings hope to anti-angiogenesis and anti-vascular treatments. When administered intravenously, they can also be selectively delivered to the lung and liver.