In gene delivery, non-viral vectors have become the preferred carrier system for DNA delivery. They can overcome major viral problems, such as immunogenicity and mutagenicity. Cationic lipid-mediated gene transfer is one of the most commonly used non-viral vectors and has been shown to be a safe and effective vector. [Cationic liposome](https://www.creative-biolabs.com/lipid-based-delivery/cationic-liposome-development-service.htm) is a structure made of positively charged lipids. Because of their good interaction with negatively charged DNA and cell membranes, they are increasingly being studied for gene therapy. They have demonstrated their selectivity to tumor vascular endothelial cells, which brings hope to anti-angiogenesis and anti-vascular treatments. When administered intravenously, they can also be selectively delivered to the lung and liver.

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